Organ Function . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7-1
Organ function
Synthesis and clearance
Absorption
Homeostatic systems
Protein-bound transport in blood
Nutritional Status. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8-1
Nutrients
Trace minerals and vitamins
Tissue Injury. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9-1
Markers of cellular damage
Immunologic injury
Infection
Genetic Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10-1
Chromosome abnormalities
DNA mutation
Screening for genetic disease
Reproduction and genetic disease
C
ancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11-1
Markers of cancer
Diagnosis
Management
Drug Therapy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12-1
The laboratory in drug therapy
Drug disposition
Monitoring therapy and adjusting the dosing regimen
Drug toxicity
Appendix: Specimen collection procedures . . . . . . . . . . . . . . . . . A-1
Blood, arterial: radial artery
Blood venous: antecubital vein
Bone marrow: posterior iliac crest aspiration and biopsy
Cerebrospinal fluid: lumbar subarachnoid space
Peritoneal fluid
Pleural fluid
Urine: timed collection
Urine: random collection
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
